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Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 1-17 doi: 10.1007/s11684-016-0439-x

Abstract:

Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolismLF can be classified into acute LF, acute-on-chronic LF (ACLF), and chronic LF.

Keywords： liver failure     chronic liver failure     acute-on-chronic liver failure     diagnosis     prognosis     treatment    

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Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract:

The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively.His liver function deteriorated, yielding Child-Pugh grade C and reaching a model for end-stage liverperiod; this condition was complicated with highly active variceal bleeding and coagulation system failurePiggyback orthotopic liver transplantation was performed as the final treatment.

Keywords： acute-on-chronic liver failure     submassive necrosis     viral hepatitis B     esophageal variceal bleeding     liver    

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Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 15-19 doi: 10.1007/s11684-010-0110-x

Abstract:

Acute liver failure remains a significant cause of morbidity and mortality.Bioartificial liver (BAL) devices have been in development for more than 20 years.patients’ own liver has recovered or a donor liver becomes available for transplant.In conclusion, BAL is, in principle, an important therapeutic strategy for patients with acute liverfailure, and may also be a bridge to liver transplantation.

Keywords： acute liver failure     bioartificial livers     hepatocyte     bioreactor    

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patientsto get a regression formula for standard liver volume (SLV) and BSA.It turned out that the mean liver volume of the control group was 1 058±337 cm3.Child A, B level was not reduced, but in Child C level it was significantly reduced with the lowest liverIn conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver

Keywords： liver volume variation     cirrhosis     acute liver failure (ALF)    

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Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 167-172 doi: 10.1007/s11684-007-0031-5

Abstract: An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) afterliver transplantation has not been established previously.This study involved 62 subjects who underwent liver transplantation.IAH impaired renal function and was an independent risk factor for ARF after liver transplantation.
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Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 271-276 doi: 10.1007/s11684-009-0054-1

Abstract: between hepatitis B virus (HBV) DNA levels during the course and the progression to cirrhosis with chronicA total of 239 chronic hepatitis B patients confirmed by liver biopsy between 2001 and 2007 were followedProgression to cirrhosis in chronic hepatitis B patients is correlated with HBV-DNA levels during follow-up

Keywords： hepatitis B     chronic     viral load     liver cirrhosis    

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Advances in some common chronic liver diseases

Ke-Qin Hu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 127-128 doi: 10.1007/s11684-014-0341-3

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

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Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL Article

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Engineering 2022, Volume 14, Issue 7,   Pages 134-146 doi: 10.1016/j.eng.2020.12.013

Abstract:

Acute liver failure (ALF) has an abrupt onset with a frequently fatal outcome.Previous studies have found that oral antibiotics prevent drug-induced liver injury in animal experimentssequencing showed that inflammatory responses were inhibited and metabolic pathways were upregulated in the liver

Keywords： Gut microbiota     Antibiotic     Tryptophan     Kynurenine     Aryl hydrocarbon receptor     Acute liver failure    

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FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 295-305 doi: 10.1007/s11684-021-0857-2

Abstract: The association among plasma trimethylamine-N-oxide (TMAO), FMO3 polymorphisms, and chronic heartfailure (CHF) remains to be elucidated.

Keywords： chronic heart failure     trimethylamine-N-oxide     flavin monooxygenase 3     single nucleotide polymorphism    

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Clinical analysis of 275 cases of acute drug-induced liver disease

LI Lei, JIANG Wei, WANG Jiyao

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 58-61 doi: 10.1007/s11684-007-0012-8

Abstract: analyze the causative drugs, clinical manifestation and pathological characteristics of the patients with acutedrug-induced liver disease, from January 2000 to December 2005, 275 cases diagnosed as acute drug-inducedIn 41 cases, the diagnosis was confirmed by liver biopsy.The proportion of acute drug-induced liver disease among all of the acute liver injuries was annuallyThe most common drugs which induced acute liver injuries were traditional Chinese herb medicine (23.3%
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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract:

Liver transplantation is a conventional treatment for terminal stage liver diseases.Intestinal barrier destruction is widely observed among patients receiving liver transplant and sufferingThis article reviews the research progress for gut microbial alterations and liver transplantation.microbial alteration and the prediction of possible injuries utilizing microbial alteration during liverand offer a hypothesis on the utilization of microbial alteration in liver transplantation.

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 111-125 doi: 10.1007/s11684-021-0854-5

Abstract: Although mixed liver impairment has been reported in COVID-19 patients, the association of liver injurycaused by specific subtype especially chronic hepatitis B (CHB) with COVID-19 has not been elucidatedIn addition to previously reported liver impairment markers, such as alanine aminotransferase, aspartate

Keywords： COVID-19     chronic hepatitis B     liver injury     coagulation dysfunction    

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Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 127-130 doi: 10.1007/s11684-010-0009-6

Abstract: The surgical emergency treatments and curative effects of postrenal acute renal failure following obstructionOf the 13 infants with postrenal acute renal failure following obstruction due to upper urinary calculicatheterization of the ureter with ureteroscopy is a minimally invasive, safe and effective therapy for postrenal acuterenal failure following obstruction due to upper urinary calculi in infants.

Keywords： infant     acute renal failure     postrenal     ureteroscopy    

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Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidenticalhematopoietic stem cell transplantation in acute myeloid leukemia

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 667-679 doi: 10.1007/s11684-019-0702-z

Abstract: Chronic graft-versus-host disease (cGVHD) is a major complication following unmanipulated haploidenticalidentify the risk factors for cGVHD in patients who underwent anti-thymocyte globulin-based haplo-HSCT for acuteThe patients who had grades III to IV acute GVHD (aGVHD) had higher 8-year incidence of cGVHD (total,

Keywords： acute graft-versus-host disease     chronic graft-versus-host disease     National Institutes of Health consensuscriteria     acute myeloid leukemia     anti-thymocyte globulin    

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Title Author Date Type Operation

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article

Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Journal Article

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Journal Article

Advances in some common chronic liver diseases

Ke-Qin Hu

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Journal Article

FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Journal Article

Clinical analysis of 275 cases of acute drug-induced liver disease

LI Lei, JIANG Wei, WANG Jiyao

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Journal Article

Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Journal Article

Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidenticalhematopoietic stem cell transplantation in acute myeloid leukemia

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

Journal Article